A Study of Correlation between Body Mass Index and Median Nerve Conduction in Type II Diabetes Mellitus Subjects
There is a world-wide increase in the prevalence of Diabetes Mellitus and it is associated with an increase in obesity. As the adipose tissue in epineurium is related to some extent to amount of body fat, it is possible that the amount of such fat may affect the nerve conduction. In this study, we have analyzed effect of Body Mass Index (BMI, Group Obese) on various parameters of Median nerve conduction study in one hundred twenty three Type II diabetes mellitus subjects. All Type II diabetes mellitus subjects who recruited from OPD of the Department of Medicine, National Institute of Medical Sciences and research, Hospital, NIMS University Jaipur. All the subjects are on hypoglycemic medicine. BMI was determined and standardized protocol was followed while performing Nerve conduction study (NCS) in all the subjects. Medicaid System’s EMG/NCV equipment with Neurostim software was used for nerve conduction velocity. Prolongation of distal latency (DL) and reduced the amplitude and conduction velocity highly significant in Type II diabetes mellitus subjects sensory and motor median nerve. Higher BMI or in obese Type II diabetes mellitus subjects was found to be non-significantly associated with all parameters of median nerve. The distal latency negatively correlated and amplitude and conduction velocity positively correlated with body mass index of sensory median nerve but amplitude negatively correlated and distal latency and conduction velocity positively correlated with body mass index of motor median nerve.
This study demonstrated that various parameters of nerve conduction study can be affected by BMI. So, this biological factor has to be taken into consideration while interpreting nerve conduction studies.
Keywords - Type II Diabetes Mellitus, Body Mass Index, Nerve Conduction Study, Distal Latency.