Paper Title
An Evaluation of Antibacterial Potential of Oyster Mushroom (Pleurotus sp.) against some Pathogenic Bacteria Staphylococcus Aureus, Bacillus Cereus, Escherichia Coli, Pseudomonas Aeruginosa, Salmonella Typhi and Proteus Vulgaris

This study illustrates The bactericidal activity of Four totally different solvent extracts of Pleurotus sp were taken like Ethyl acetate, Benzene, Chloroform, Hexane and their concentrations varried as 50mg/ml,100mg/ml,150mg/ml,200mg/ml. Medication activities of totally different solvents were tested against different microorganism by exploitating disc diffusion technique. The Chloroform extract was more practical against microorganism. the uppermost medication activity of chloroform extract of Pleurotus sp. was found at 39.0± 3 mm against Proteus vulgaris(400mg/ml)and minimum found ethyl acetate extract(50mg/ml) at19.6 ± 2 against Pseudomonas aeruginosa. The results provided proof that the chloroform extracts of Pleurotus sp might so be robust potential sources of natural inhibitor and medication agents against those pathogenic microrganism. Introduction - Pleurotus species is one of the choice edible mushrooms which could be cultivated in many countries at intervals the subtropic and temperate zones. typically 'Pleurotus', aforesaid as ‘oyster mushroom’ over the earth whereas in China it's known as univalve mushroom’ and ‘Dhingri’ in Asian country Common name is oyster mushrooms (English), toadstool (bengali), kukuramutta, gagandhul (hindi), puttakukka (tamil), anabe (kannada), puttagodugu (telegu). Pleurotusspecies are utilized by the oldsters in all over the earth for his or her organic process price, healthful properties and different useful effects [1].The plant part of the mushroom is to boot a attainable offer of compound and phenol degrading enzymes [2].Both plant part and conjointly the natural object of this mushroom contain compounds with wide-ranging antimicrobial activity and their compounds are often isolated from many mushrooms species and can be of profit for human. Mushroom species unleash varied bioactive compounds like terpenoids, flavonoids, tannins, alkaloids, and polysaccharides [3,4]. Mushrooms unit of measurement immensely created in bioactive compounds but principally untapped resource of useful natural compounds. These bioactive compounds unit of measurement found in varied cellular elements and secondary metabolites, that are isolated and well-known from the mature bodies [5]. The mature bodies and natural object of mushrooms exhibit health promoting values like immune stimulatory, medication, and antioxidative properties [6]. The synergistic impact of these substances would supply potential therapeutic values. There square measure man kind of healthful mushrooms, like Aleurodiscus, Coprinus, Clitocybe, Daedalea, Marasmius,Merulius, Pleurotus, Polyporus, Poria, Psathyrella, and Tricholomaspp., that are sensible sources of ß-glucan, lectin, phenolic compounds, flavonoids, polysaccharides, triterpenoids, diateryfibre, lentinan, schizophyllan, vitamin ,lovastatin, pleuran, steroids, glycopeptides, terpenes, saponins, xanthones, coumarins, alkaloid, purine, purimidine, kinon, fenilpropanoid, kalvasin, volvotoksin, flammutoksin, porisin, eryngeolysin etc. they are created sources of natural antibiotics, where the cell wall glucans unit of measurement normal for immune modulatory properties and much of of the externalized secondary metabolites combat microorganism, fungi and viruses [7,8,9,10,11,12,13]also square measure used extensively in ancient medication for solidifying varied types of diseases like antimicrobial, inhibitor, antiviral, anticancer, antitumor, medicament, vas diseases, immune modulating, central activities etc.,[14,15,16,]. Medically Plerotus ostreatus are reportable to decrease steroid levels vi. The stem of the mushroom is to boot a attainable offer of compound and phenol degrading enzymes [17]. it's to boot used industrially as a bio remediator[18,19]. In recent times they have to boot attracted nice attention as a offer of bioactive metabolites for the event of drugs and nutraceuticals [20,21]. variety of them have to boot been found to be a offer of secondary metabolites like phenolic compounds, flavonoids, terpenoids, sterols, vitamin, ergothioneine and carotenoids. They exhibit high substance properties which they so keep off cancers, HIV-1 AIDS and different agent ailments; they are antimutagenic, anti-tumor and could be accustomed manage vas disorders [22]. analysis has shown that prime amounts of antioxidants would possibly stop aerobiotic stress caused by free radicals that cause cell injury, generation of somatic cell and vegetative cell aging [23] aerobiotic stress might occur as a results of either the presence of oxidisation agents, decrease at intervals the extent of antioxidants or every factors. at a lower place such circumstances, reactive substance species (ROS) and free radicals unit of measurement created as harmful by-products of oxidization methodology. many investigations from utterly completely different region of the earth confirmed that the fungus genus mushroom having high nutrition to boot contains varied bioactive compounds in addition as terpenoids, steroids, phenols, alkaloids, lections and nucleotides that square measure isolated and well-known from the fruit body, natural object and culture broth of mushrooms and unit of measurement shown to possess promising biological effects [24]. Not teeming literature is accessible with respect to their medication activities of Pleurotussp. it had been so the aim of this gift study to screen Pleurotus sp. for his or her medication activities. Keywords - Oyster Mushrooms; Pathogenic Bacteria; Pleurotus sp.; Zone of Inhibition.