Paper Title
Association of Epicardial Fat and Visceral Fat in CAD Patients

Abstract
Background: Anatomical location of fat depot plays a crucial role and is closely associated with the ill effects of inflammatory signaling. Epicardial fat is one of the fat depots which are in close proximity with coronary artery. The amount of total visceral fat and epicardial fat thickness might provide a clear and wider picture of the role of these fat depots with the association with atherosclerosis. The epicardial fat thickness may indicate the excessive deposition of fat on heart while total visceral fat provides the overall fat deposition in the body. The excessive deposition of fat may develop some hypertrophy of adipocyte and leads to hypoxia. It triggers some inflammatory cascades and may result in atherogenesis and CAD. Aim: Aim of the present study was to determine the association of epicardial fat thickness and visceral fat in CAD patients. Results: The study results observed an increased visceral fat content in CAD patients as compared to controls [9.8 (± 2.98)] and [8.35 (± 2.58)]. Epicardial fat content was also increased in CAD patients as compared to controls. A significant difference was observed for Epicardial fat thickness [7.2 (±1.15 mm) / 3.6 (± 0.83) mm]. The study also found connection /association between visceral fat and epicardial fat of CAD patients. Conclusion: The current study concluded that visceral fat and epicardial fat both are increased in CAD patients as compared to controls with a link between them. Keywords - CAD(Coronary Artery Disease), Epicardial Fat , Visceral Fat