Paper Title
Uterine Artery Doppler Prediction of Preeclampsia and Adverse Foetal & Maternal Outcome

Abstract
Background: Hypertensive disorders complicating pregnancy are common. Pre-eclampsia & eclampsia are major causes of maternal morbidity and mortality, particularly in developing countries. With prompt recognition of symptoms and early diagnosis of preeclampsia can lead to improved maternal and neonatal outcome. Numerous tests have been proposed for the prediction of preeclampsia, their results have been inconsistent. We focused to investigate the uterine artery by conducting Doppler ultrasound study in predicting the preeclampsia in women with a high-risk pregnancy. Materials and Methods: This prospective cross-sectional observational study was conducted on 195pregnant women referred to Acharya Vinoba Bhave Rural Hospital, Wardha (India). Uterine artery Doppler was conducted on allwomen with raised blood pressure referred to the radiology department. The patients were followed-up and outcomes (such as eclampsia, chronic hypertension, death, Neonatal Intensive Care Unit admission, low birth weight, preterm labour, etc.) association with preeclampsia was measured. Results: The mean age of pregnant women was 26.47 ± 4.96 years old. Preeclampsia was seen in 68 (34.9%) of the women. In the study maternal outcome such as eclampsia and maternal HTN was significantly associated with Preeclampsia. Similarly neonatal outcome such as Low birth weight, NICU admission and IUGR was significantly associated with Preeclampsia .Pulsatility Index (PI) at >1.2 had highest sensitivity of 64.71%, specificity of 71.65%, PPV of 55% and NPV of 79.1% to predict preeclampsia than any other doppler indices. Conclusion: The findings of this study suggests that PI at >1.2 had better validity in predicting Preeclampsia compared to Resistive Index (RI) and Standard deviation (SD).