PREDICTIVE RELEVANCE OF OPTICAL COHERENCE TOMOGRAPHY INDICES IN CONJUNCTION WITH VISUAL ACUITY AND SURGICAL OUTCOMES OF IDIOPATHIC MACULAR HOLE
Abstract - Idiopathic macular hole (IMH) is a disorder that mainly occurs from many forces interacting with the fovea, most notably ongoing vitreous tension in the tangential and anteroposterior orientations.The latest study has emphasized the importance of microincision vitrectomy surgery (IMH) and this type of surgery is carried out with a minimum invasiveness, vision recovery was more often the result. The main purpose of this research study was basically to determine how visual acuity and pre-operative optical coherence tomography (OCT) indices linked to IMH closure following surgery. The study's main conclusions were linked to diagnostic characteristics such as OCT indices, variations in best-corrected visual acuity (BCVA), clinical parameters related to IMH closure, and predictive variables that influence visual outcomes. Stepwise regression analysis was performed on each OCT variable, taking into account intervention aspects that are known to predict the need for IMH closure. Our studyrevealed thatthe hole form factor (HFF), macular hole index (MHI), and tractional hole index (THI) have a positive correlation with post-operative visual acuity. However, basal hole diameter (BHD) and minimum hole diameter (MHD) have a negative correlation. Out of them only HFF, MHI, BHD, and MHD were observed to be statistically significant (p<0.05). The mean baseline value BCVA was 0.75±0.44 logMAR (Logarithm of the Minimum Angle of Resolution) units, which was improved to 0.29±0.27 logMAR units at the final follow-up andthe surgical success closure rate of IMH was 100%. In conclusion, our findings suggest that OCT metrics could potentially be used as a single key index for assessing the IMH closure rate, andwere found to be essential markers as well as safe and efficient predictors of visual outcome in IMH.
Keywords - Idiopathic Macular Hole, Visual Outcomes, Optical Coherence Tomography