Paper Title
Assessment of Diffusion Characteristics in Intracranial Tumours Using Diffusion-Weighted Imaging (DWI) and Apparent Diffusion Coefficient (ADC) Mapping
Abstract
Magnetic Resonance Imaging (MRI) is a widely used non-invasive technique for evaluating brain lesions, offering detailed structural information. However, conventional MRI often has limitations in distinguishing between tumor components, perilesional edema, and healthy brain tissue. Diffusion-Weighted Imaging (DWI), an advanced MRI technique, assesses the movement of water molecules within tissues, providing additional insights.This study aimed to analyze the diffusion characteristics of different components of intracranial tumors using DWI.A total of 40 patients with intracranial tumors underwent both conventional MRI and DWI. Imaging was performed using an echo-planar diffusion imaging protocol, with apparent diffusion coefficient (ADC) maps generated. Absolute ADC values were calculated for tumor components, perilesional edema, and normal brain tissue.The primary extra-axial lesion observed was meningioma, which showed higher ADC values compared to normal brain tissue. The main intra-axial lesions were gliomas, with a mean ADC of 1.2 ± 0.69 × 10⁻³ mm²/s.DWI is a valuable non-invasive imaging modality for the diagnosis and characterization of various intracranial neoplasms, providing enhanced differentiation between tumor components and surrounding tissues.
Keywords - Diffusion Weighted Imaging (DWI), Apparent Diffusion Coefficient (ADC), intra axial lesions, extra axial lesion