Paper Title
A REVIEW ON ROLE OF PLANT SECONDARY METABOLITES IN SUPPRESSION OF DISEASE- ASSOCIATED PROTEIN

Abstract
Plant secondary metabolites are a rich array of bioactive compounds produced as secondary products of plant metabolism, not crucial for growth and development, but for ecological interactions and protection. In contrast to primary metabolites like amino acids and nucleotides, these are involved in the defence against pathogens, pests, and stress. The last few years have seen a significant increase in the recognition of plant secondary metabolites for their therapeutic potential in inhibiting disease-related proteins in inflammation, hyperglycemia, dyslipidemia and other chronic diseases. They have inhibitory effects on specific molecular targets, making them potential leads for drug development. These metabolites interact with disease-associated proteins such as TNF-α, COX-2, p53, EGFR to regulate inflammation, metabolic, neurodegenerative disease, and cancer. This review brings together recent knowledge on the classification and modes of action of plant secondary metabolites on disease-associated proteins and highlights their growing importance in medicine and industry. Keywords - Plant, Secondary Metabolite, Classification, Medicine, Anti-Inflammatory, Disease-Associated Protein