Paper Title
Evaluation of Anxiolytic Activity of Rousvastatin in Male Albino Mice

Abstract
Objectives - To assess the anxiolytic activity of ROUSVASTATIN in male albino mice. To compare the anxiolytic activity of ROUSVASTATIN with standard drug as diazepam . Materials and methods - The study was conducted in Pharmacology Department , j j m medical college. Rousvastatin and Diazepam were dissolved in saline. Control group mice were injected with saline. Drugs and saline were injected intraperitoneally. Results - In elevated plus maze Rousvastatin at dose 30 mg/kg and 50mg/kg increased number of open arm and total arm entries, time spent in open arm and decreased time spent in closed arm. Conclusion - The results suggest that the significant dose-dependent antianxiety activity of Rousvastatin is similar to the behavioural effects of Diazepam. Keywords - Anxiolytic activity, Rousvastatin, Diazepam.