Paper Title
The Coronavirus Disease (Covid-19): Prevention or Cure? An Exception
Abstract
This study aims to evaluate mechanism of action of spread of Coronavirus infection in relation to human physiology and to prevent further occurrence of disease and spread in human population. Coronavirus disease emerged as a global pandemic across several countries causing huge morbidity and mortality and was declared as a public health emergency by the WHO. This disease is caused by a pleomorphic s-s RNA virus having surface projections which is similar to SARS Covid-2 with bats as their primary reservoir. The incubation period is 2-14 days. Primary transmission is local resulting from droplet spread and aerosols from infected individuals. Clinical symptoms range from sorethroat, fever not relieved by routine antibiotîcs and breathlessness progressing to dyspnoea. Evaluation of samples of sputum and nasopharyngeal secretions demonstrate positive nucleic acid of SARS-Covid-2 strain. High risk factors include the elderly, people with underlying disease or patients on immunosuppressive drugs such as steroids. Laboratory diagnosis demands the need for molecular test. Findings show decreased lymphocyte and plate count along with raised ESR.Use of facemask and regular handwashing and personal protective equipment such as hand sanitiser is mandatory to prevent infection. Use of certified N95 mask by healthcare workers is advised to prevent spread of nosocomial infections. As disease cannot be treated by routine antibiotics, antiviral drugs such as Ribavirin seem palliative. Further research including vaccination still needs to be demonstrated with respect to treatment and outcome of the coronavirus infection.