Paper Title
A Study on Prediction of Coronary Artery Disease Severity Using Cha2ds2 VASC Scoring System in Acute Coronary Syndrome Patients

Abstract
BACKGROUND Atherosclerotic cardiovascular disease, especially coronary artery disease remains the leading cause of death world wide. The development and progression of atherosclerotic CVD is often insidious and may appear without any warning signs and symptoms. For these reasons, early detection of the risk population and commencing prevention strategies is an important aspect in the treatment of CVD. Therefore, the CHA2DS2-VASc, scoring systems may play an important role as predictive model because the parameters of this scoring system includes similar risk factor for development of coronary artery disease. AIM OF THE STUDY To study the correlation between CHA2DS2 VASc score and angiographic severity of coronary artery disease by number of vessels involved. MATERIALS AND METHODS 122 Patients with acute coronary syndrome diagnosed based on ECG or ECHO evidence and admitted in ICCU of KIMS Hubli, and undergoing coronary angiography during the study period were taken in the study considering the inclusion and exclusion criteria. Each patient was evaluated with History, clinical examination, and lab investigations which included: Electrocardiogram, 2D-ECHO, Coronary angiography, HbA1c, Lipid profile and Renal function test. Based on angiographic findings, coronary artery disease severity was assessed by number of vessels involved and it was compared to CHA2DS2 VASc score and the data obtained was analysed by different statistical methods. RESULTS Out of 122 patients in the study, chest pain was the most common presenting symptom. Inferior wall STEMI was the most common ECG finding in our study(33.3%). And the most common risk factors was systemic hypertension. The mean CHA2DS2 VASc score among patients with SVD Was 1.15, among DVD was 1.7 and among patients with TVD was 2.64. As the CHA2DS2 VASc Score increases the number of vessels involved in angiography also increases. Indicating more severe disease in patients with high CHA2DS2 VASc score. CONCLUSION From this study we can conclude that, the CHA2DS2 VASc score is a cost effective and easily reliable score for predicting the severity of coronary artery disease, which can be routinely applied in clinical practice.